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QS. An Nahl, 16:68
• Dan Tuhanmu mewahyukan kepada
lebah: "Buatlah sarang-sarang di bukitbukit, di pohon-pohon kayu, dan di
tempat-tempat yang dibikin manusia",
QS. An Nahl, 16:69
• kemudian makanlah dari tiap-tiap (macam) buahbuahan dan tempuhlah jalan Tuhanmu yang telah
dimudahkan (bagimu). Dari perut lebah itu keluar
minuman (madu) yang bermacam-macam warnanya,
di dalamnya terdapat obat yang menyembuhkan bagi
manusia. Sesungguhnya pada yang demikian itu
benar-benar terdapat tanda (kebesaran Tuhan) bagi
orang-orang yang memikirkan.
• Betina
Jantan
Betina
…(madu) yang bermacam-macam
warnanya…
…(madu) yang bermacam-macam
warnanya…
Awet Ribuan Tahun
Ribuan Tahun Masih Layak Konsumsi
Super-Food: Nirkadaluarsa & Obat Mujarab
2. Hidrogen
Peroksida

3. Tingkat
Keasaman
1. Kadar
4. Peptida
Antikuman
6. Mikroba
Gula
Probiotik
5. Zat
Fenolik
1. Kadar Gula: ±70-80%
1. Kadar Gula: ±70-80%
1. Kadar Gula: ±70-80%
+ 22 Gula lebih kompleks lainnya
TABLE 2.-Carbohydrate composition of honey types
Number
of samples
23
25
5
3
3
5
4
26
3
3
3
10
3
6
3
2
2
3
5
2
3
3
Floral
type
Alfalfa
Alfalfa-sweetclover
Aster
Basswood
Blackberry
Buckwheat
Buckwheat, wild
“Clover“
Clover, alsike
Clover, crimson
Clover, Hubam
Cotton
Fireweed
Gallberry
Goldenrod
Heartsease
Holly
Honeydew, cedar
Honeydew, oak
Horsemint
Locust, black
Loosestrife, purple
Dextrose
Levulose
Percent
33.40
33.57
31.33
31.59
25.94
29.46
30.50
32.22
30.72
30.87
33.42
36.74
30.72
30.15
33.15
32.98
25.65
25.92
27.43
33.63
28.00
29.90
Percent
39.11
39.29
37.55
37.88
37.64
35.30
39.72
37.84
39.18
38.21
38.69
39.28
39.81
39.85
39.57
37.23
38.98
25.16
34.84
37.37
40.66
37.75
Sucrose
Percent
2.64
2.00
.81
1.20
1.27
.78
.79
1.44
1.40
.91
.86
1.14
1.28
.72
.51
1.95
1.00
.68
.84
1.01
1.01
.62
Maltose
Percent
6.01
6.30
8.45
6.86
11.33
7.63
7.21
6.60
7.46
8.59
6.23
4.87
7.12
7.71
6.57
5.71
10.07
6.20
10.45
5.53
8.42
8.13
Higher
Sugars
Percent
.89
.91
1.04
1.44
2.50
2.27
.83
1.39
1.55
1.63
.74
.50
2.06
1.22
.59
.53
2.16
9.61
2.16
.73
1.90
2.35
1. Kadar Gula
Larutan Gula 70-80%
Dehidrasi
Osmosis

Super-Food: Nirkadaluarsa & Obat Mujarab
2. Hidrogen
Peroksida

3. Tingkat
Keasaman
1. Kadar
4. Peptida
Antikuman
6. Mikroba
Gula
Probiotik
5. Zat
Polifenolik
Hidrogen Peroksida (H2O2)
Hidrogen Peroksida (H2O2)
(dari nektar)
(dalam perut lebah)
H2O + O2
Sukrosa
(dari nektar)
Invertase
(dalam perut lebah)
(dalam perut lebah)
Glukosa oksidase
Glukosa oksidase
Glukosa
Asam glukonat +
Hidrogen peroksida
H2O + O2
Glukosa + Fruktosa
Hidrogen Peroksida (H2O2)
Hidrogen peroksida/
Dihidrogen dioksida
(H2O2)
Air/
Didrogen oksida
(H2O)
Hidrogen Peroksida (H2O2)
+
energi panas
Hidrogen peroksida/
Dihidrogen dioksida
(H2O2)
Bahan bakar roket
Pemutih gigi, rambut
Pembersih kuman
Obat kumur
Pemutih industri kertas,
detergent,

Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen
Peroksida

3. Tingkat
Keasaman
1. Kadar
4. Peptida
Antikuman
6. Mikroba
Gula
Probiotik
5. Zat
Polifenolik
3. Tingkat Keasaman
• pH madu = 3 – 4,5
• Sekitar 18 jenis asam:
• asam format, asam asetat,
asam butirat, asam laktat,
asam oksalat, asam suksinat,
asam tartarat, asam malat,
asam piruvat, asam
piroglutamat, asam aketoglutarat, asam glukollat,
asam sitrat, asam maleat, asam
2- atau 3-fosfogliserat, asam aatau B-gliserofosfat, dan
glukosa fosfat.
Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen
Peroksida



3. Tingkat
Keasaman
1. Kadar
4. Peptida
Antikuman
6. Mikroba
Gula
Probiotik
5. Zat
Polifenolik
4. Peptida Antikuman: “Bee Defensin”
4. Peptida Antikuman: “Bee Defensin”
• Figure 2. Electron micrographs of negatively stained Bacillus
subtilis either untreated (A) or treated by lucifensin (Lucilia
sericata’s defensin) for 60 min (B). Scale bars represent 1 µm.
Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen
Peroksida



3. Tingkat
Keasaman
1. Kadar
4. Peptida
Antikuman
6. Mikroba
Gula
Probiotik
5. Zat

Polifenolik
6. Mikroba Probiotik
5. Zat Polifenolik
• could serve as a good source of natural
antioxidants effective in reducing the risk of
the occurrence of
– heart disease,
– cancer,
– cataracts,
– different inflammatory processes and
– immuno-system decline.
Super-Food: Nirkadaluarsa & Obat Mujarab

2. Hidrogen
Peroksida




3. Tingkat
Keasaman
1. Kadar
4. Peptida
Antikuman
6. Mikroba
Gula

Probiotik
5. Zat
Polifenolik
6. Mikroba Probiotik
• Alejandra Vasquez, a researcher at Lund
University:
• In wild and fresh honey, which honey hunters collect
from bees’ nests in high cliffs and trees, there are billions
of healthy lactic acid bacteria of 13 different types. This is in
comparison with the 1-3 different types found in
commercial probiotic products, she explains.
• The honey bees have used these bacteria for 80 million
years to produce and protect their honey and their bee
bread (bee pollen), which they produce to feed the entire
bee colony. The researchers have now also shown that the
healthy lactic acid bacteria combat the two most serious
bacterial diseases to affect honey bees.
http://www.lunduniversity.lu.se/o.o.i.s?news_item=5820&id=24890
•
•
Figure 2. In vitro visualization of lactobacilli.
In vitro visualization of lactobacilli attached to the wall of a honeybee crop using SEM.A, B and C show
different areas of a honey crop at similar magnification with visible attachment structures resembling
extracellular polymeric substances (EPS). D shows a larger part of the crop with attached bacteria.
Photographer Lennart Nilsson.
doi:10.1371/journal.pone.0033188.g002
Vásquez A, Forsgren E, Fries I, Paxton RJ, et al. (2012) Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees. PLoS
Figure 3. In vivo visualization of LAB biofilm.
The red fluorescence shows live-stained bacteria in a LAB biofilm attached to a honey crop. The green fluorescence
shows the nuclei of the honeybee crop cells. The visualized tissue shows a projection of 112 confocal z-sections
(through a 37.6 µm z-depth, covering a xy-area of 246×246 µm).
Vásquez A, Forsgren E, Fries I, Paxton RJ, et al. (2012) Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees. PLoS
ONE 7(3): e33188. doi:10.1371/journal.pone.0033188
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033188
Figure 4. LAB rescue of honeybee larvae from European Foulbrood.
Proportion dead larvae in both replicates (total number dead after 21 days). Data presented as a mean for the
three groups fed M. plutonius (107, 106 and105 bacteria ml−1), and the 3 groups fed M. plutonius and LAB.
Irrespective of infectious dose, the overall effect from the LAB supplement was a significantly reduced mortality in
the treated groups. Mortality in the uninfected control groups was <7%.
Vásquez A, Forsgren E, Fries I, Paxton RJ, et al. (2012) Symbionts as Major Modulators of Insect Health: Lactic Acid Bacteria and Honeybees. PLoS
ONE 7(3): e33188. doi:10.1371/journal.pone.0033188
http://www.plosone.org/article/info:doi/10.1371/journal.pone.0033188
…di dalamnya terdapat obat yang
menyembuhkan bagi manusia…
• Neonatal IV infiltrate treated with
medical grade honey
• Traumatic leg wound in teen – treated with
medical honey, wound vac and collagen.
Before and after shot of topical honey treatment for 3
weeks. You're welcome. Adapted from Efem (1988)
• Workers package Medihoney wound and burn dressing at the Derma
Sciences manufacturing facility in Toronto.
Kelebihan Lain Madu Sebagai Obat Luka
•
•
•
•
•
Tidak perih
Tidak menjadikan perban merekat pada luka
Tidak bersifat racun pada sel mamalia
Melawan beragam jenis mikroba penyakit
Tidak memicu kekebalan mikroba penyakit
Sekian