ABSTRACT Background Foot diabetic is a complex and chronic wound which has an impact on the morbidity and mortality of the patient. Foot diabetic ulcer is a port de entry of microorganism to penetrate and infect the body and can cause sepsis shock which is characterized by persistent hypotension and increased body temperature which requires a vasopressor to maintain MAP ≥ 65 mmHg and serum lactate levels> 2 mmol / L (18 ng / dL) Aim : To achieve better management of sepsis shock in DM Patient in UKI Hospital Case Description : Patient Mr. KM 60 years old was sent to ICU UKI General Hospital unconsciously, with history of type 2 DM for 5 years, ulcers in digiti I and II left lower extremity was found ,and was planned to get amputated as soon as he reaches better condition . physical examination was done with results GCS E2M3V2 temperature of 38.9 C, blood pressure 80/50 mmHg, and respiratory rate 33x / minutes, qSOFA 3. Intervention : Patient was administered broad spectrum antibiotics, norepinephrine, and ventilator V-SIMV is being installed. Novorapid injection was given to maintain the blood sugar level. Conclusion : The management of sepsis shock in patient is expected to increase the ASA of patients who were previously ASA 5 to ASA 2 to make the patient capable to get anesthetized and undergo amputation procedure to get rid of the source infection. Keywords : foot diabetic, sepsis shock , qSOFA