VP AIRWAY MANAGEMENT 1. Anatomy a. Upper airway: pharynx, nose, mouth, larynx, trachea, main-stem bronchi b. There are two openings to the human airway: the nose (leads to nasopharynx) and the mouth (leads to oropharynx). They are separated anteriorly by the palate c. Pharynx is a U-shaped fibromuscular structure that extends from the base of the skull to the cricoid cartilage at the entrance to the esophagus. d. Nasopharynx is separated from the oropharynx by an imaginary plane that extends posteriorly e. The epiglottis functionally separates the oropharynx from the laryngopharynx and prevents aspiration by covering the glottis when swallowing. f. The larynx is a cargilaginous skeleton held by ligaments and muscles. It is composed of nine cartilages: thyroid (shields conus elasticus which forms vocal cord), cricoid, epiglottic, and (in pairs) arytenoid, corniculate, and cuneiform. g. Sensory supply: i. Mucous membranes of nose: CN V.1 anteriorly and V.2 posteriorly ii. Superior and inferior surface of hard and soft palate: palatine nerves iii. Nasal mucosa: CN I iv. Anterior 2/3 of tongue: CN V.3 with branches of CN VII, Posterior 1/3 of tongue: CN IX v. Superior laryngeal branch of vagus nerve divides into: 1. External (motor) nerve (cricothyroid muscle) 2. Internal (sensory) laryngeal nerve Provides sensory supply to the larynx between epiglottis and vocal cords vi. Recurrent laryngeal nerve: innervates larynx below the vocal cords and trachea 1. Innervates the muscles of larynx except the cricothyroid muscle VP h. Effects of laryngeal nerve injuries: i. Unilateral denervation of cricothyroid muscle: very subtle clinical findings ii. Bilateral palsy of superior laryngeal nerve: hoarseness, airway still fine iii. Unilateral paralysis of recurrent laryngeal nerve: paralysis of ipsilateral vocal cord -> deterioration of voice quality iv. Assuming intact superior laryngeal nerve, acute bilateral recurrent laryngeal nerve palsy -> stridor and respiratory distress because of tension of cricothyroid muscle. Chronic bilateral recurrent laryngeal nerve loss rarely provide airway problems due to compensatory mechanisms (such as atrophy of laryngeal musculature) v. Bilateral injury to vagus nerve affects superior and recurrent laryngeal nerves -> flaccid midpositioned vocal cords with impairment of phonation and airway control is of no problem i. Blood supply to the larynx: i. Branches of the thyroid arteries ii. Cricothyroid artery from the superior thyroid artery j. Trachea begins beneath the cricoid cartilage and extends to the carina -> anteriorly the trachea consists of cartilaginous rings, posteriorly it is membranous. 2. Routine airway management: a. Airway assessment b. Preparation and equipment check c. Patient positioning d. Preoxygenation e. Bag and Mask Ventilation (BMV) f. Intubation (if indicated) g. Confirmation of endotracheal tube placement h. Intraoperative management and troubleshooting i. Extubation A. Airway Assessment a. First step in successful airway management b. Assessments include: i. Mouth opening: incisor distance of 3cm or greater is desirable in adult ii. Upper lip bite test: lower teeth are brought in front of the upper teeth. This estimates the range of motion of the TMJ iii. Mallampati classification: examines the size of the tongue in relation to oral cavity. The greater the tongue obstruction the more difficult intubation may be. 1. Class 1: Entire palatal arch including the bilateral faucial pillars are visible down to their bases VP 2. Class 2: Upper part of the faucial pillars and most of the uvula are visible 3. Class 3: Only the soft and hard palates are visible 4. Class 4: Only the hard palate is visible iv. Thyromental distance: Distance between mentum and the superior thyroid notch. Distance greater than 3 fingerbreadths is desirable v. Neck circumference: greater than 27 inches is suggestive of difficulties in visualization of the glottic opening vi. Patient with morbid obesity: some may present with redundant pharyngeal tissue and increased neck circumference B. Equipment: a. The following equipment is routinely needed in airway mangement situations: i. Oxygen source ii. BMV capability iii. Laryngoscopes (direct and video) iv. Several endotracheal tubes of different sizes v. Other (not ETT) airway devices (oral, nasal airways) vi. Suction vii. Oximetry and CO2 detection viii. Stethoscope ix. Tape x. Blood pressure and electrocardiography monitors xi. IV access b. Oral and nasal airways: i. Loss of upper airway muscle tone in anesthetized patients allow the tongue and epiglottis to fall back against the posterior wall of the pharynx ii. Repositioning the head or jaw thrust is preferred technique for opening the airway iii. Awake or lightly anesthetized patient with intact laryngeal reflex may cough or even develop laryngospasm during airway insertion! VP iv. Adult oral airways: 1. Small (80mm, Guedel No. 3) 2. Medium (90mm, Guedel No. 4) 3. Large (100mm, Guedel No. 5) v. Length of nasal airway can be estimated as the distance from nares to the meatus of the ear, and should be 2-4cm longer than oral airways and lubricated. c. Face mask design and technique: i. The rim of the mask is contoured and conforms to a variety of facial features ii. Effective mask ventilation requires gas-tight mask fit and a patent airway. iii. If the mask is held with the left hand, the right hand can be used to generate positive pressure ventilation by squeezing the bag. Mask is held onto the face by thumb and index finger while the middle and ring finger grasp the bony mandible. Little finger is placed under the angle of the jaw and is used to thurst the jaw anteriorly. iv. In difficult situations, two hands may be needed to provide adequate jaw thrust and mask seal -> needs assistant to squeeze the bag or machine’s ventilator. Obstruction during expiration can be due to: 1. Excessive downward pressure from mask -> decrease pressure on mask 2. Ball-valve effect of the jaw thrust -> releasing jaw thrust during the phase of respiratory cycle VP v. Positive pressure ventilation using mask should be limited to 20cmH2O to prevent stomach inflation vi. Mask ventilation for long periods of time -> pressure injury to branches of trigeminal or facial nerves. And if face mask and mask straps are to be used for extended periods -> position should be changed to prevent injury vii. Tape the eye to minimize risk of corneal abrasions! C. Positioning: a. Relative alignment of oral and pharyngeal axis is achieved by having the patient in sniffing position b. If cervical spine pathology is suspected -> head must bekept in neutral position during all airway manipulations c. Patients with morbid obesity should be positioned on a 30 degree upward ramp, as functional residual capacity of obese patients decreases with supine position -> more rapid deoxygenation if ventilation is impaired. D. Preoxygenation: a. Preoxygenation with face mask oxygen should procede all airway mangement interventions b. O2 is delivered by masks for several minutes before anesthetic induction -> functional residual capacity (patient’s O2 reserve) is purged of nitrogen. c. Up to 90% of normal FRC of 2L following preoxygenation is filled with oxygen -> 5-8 minute oxygen reserve. d. Increasing duration of apnea without desaturation improves safety if ventilation following anesthetic induction is delayed. e. Condition that increase O2 demand (sepsis, pregnancy) and decreased FRC (morbid obesity, pregnancy) -> reduce apneic period before desaturation ensues E. Bag and Mask ventilation: a. First step in aiway management except patients undergoing rapid sequence intubation b. BMV is avoided to prevent stomach inflation -> potential for aspiration of gastric contents in nonfasted patients c. Supraglottic airway devices: consists of a tube connected to respiratory circuit or breathing bag. Common side effect is sore throat with injuries to lingual, hypoglossal, and recurrent laryngeal nerve has been reported. i. Laryngeal mask airway: 1. Helpful as life-saving temporizing measure in patients with difficult airways (cannot be ventilated or intubated) 2. Wide bore tube that connects to breathing circuit (15mm connector) and distal end is attached to elliptical cuff that can be inflated through pilot tube which is lubricated and inserted blindly to hypopharynx to perform seal around the entrance of larynx. 3. Requires anesthetic depth and muscle relaxation slightly higher than required for insertion of an oral airway 4. Ideally positioned cuff: a. Batas superior: base of tongue b. Batas lateral: pyriform sinus VP 5. 6. 7. 8. 9. 10. c. Batas inferior: esophageal sphincter If esophagus lies within the rim of the cuff -> gastric distension and regurgitation is possible Protects larynx from pharyngeal secretion but not gastric regurgitation Must remain in place until patient has regained airway reflexes -> coughing, mouth opening on command Relative contraindication: pharyngeal pathology (abscess), pharyngeal obstruction, full stomach (pregnancy, hiatal hernia), low pulmonary compliance (restrictive airway disease) requiring inspiratory pressure >30cmH20 Avoided in patients with: bronchospasm, high airway resistance Insertion can be performed under local anesthesia and bilateral superior laryngeal nerve blocks if airway needs to be secured and patient is still awake. VP 11. Variations in LMA include: a. ProSeal LMA: permits passage of gastric tube to decompress stomach b. I-Gel: gel occluder rather than inflatable cuff c. Fastrach intubation LMA: facilitate ETT through LMA d. LMA Ctrach: incorporates camera to facilitate ETT ii. Esophageal-Tracheal combitube: 1. Consists of two fused tubes, each with a 15mm connector on proximal end a. Longer blue tube has an occluded distal tip with side perforations -> forces gas to exit b. Shorter clear tube -> open tip, no side perforation 2. Usually inserted blindly through the mouth until two black rings lie between the upper and lower teeth. VP 3. Has two inflatable cuffs, 100mL proximal cuff and 15mL distal cuff which should be fully inflated after placement. a. Distal lumen lie in esophagus 95% of the time -> ventilation through blue tube will force gas to go sideways through the perforations b. Shorter clear tube: used for gastric decompression c. If it enters the trachea, ventilation through the clear tube will direct gas into the trachea iii. King Laryngeal Tube: 1. Tube with a small esophageal balloon and larger balloon for placement in hypopharynx which inflates through one inflation line 2. Lungs are inflated from air that exits from two balloons 3. If ventilation is difficult -> LT is likely inserted too deep -> slightly withdrawing the device until compliance improves ameliorates the situation F. Endotracheal intubation: employed for conduction of GA and facilitate the ventilator management of the critically ill a. Tracheal tubes: i. Most commonly made from polyvinyl chloride ii. Shape and rigidity can be altered by inserting a stylet iii. Resistance to airflow depends primarily on tube diameter but also by tube length and curvature. Size is usually designated in milimeters of internal diameter or the FRENCH STYLE (milimeters of external diameter dikali tiga) VP iv. Dilemma pemilihan tube diameter: maxinizing airflow with larger size vs minimizing trauma with smaller size v. Most adult TT have cuff inflation system which includes: 1. Valve: prevents air loss after cuff inflation 2. Pilot balloon: provides gross indication of cuff inflation 3. Inflating tube: connects valve to the cuff and is incorporated into the tube’s wall. 4. Cuff: permits positive-pressure ventilation and reduce likelihood of aspiration by creating tracheal seal. Uncuffed tubes are often used in infants and young children to minimize the risk of pressure injury and postintubation croup vi. There are two major types of cuffs: 1. High pressure (low volume): associated with more ischemic damage to tracheal mucosa, less suitable for intubation of long duration 2. Low pressure (high volume): increase likelihood of sore throat (larger mucosal contact area), aspiration, spontaneous extubation, difficult insertion (floppy cuff) -> generally employed due to lower incidence of mucosal damage vii. Cuff pressure depends on several factors: 1. Inflation volume 2. Diameter of cuff in relation to trachea 3. Tracheal and cuff compliance 4. Intrathoracic pressure (cuff pressure increase with coughing) 5. May increase during GA from diffusion of NO from trachea mucosa into the TT cuff viii. Specialized tubes: 1. Flexible tubes 2. Spiral-wound 3. Wire-reinforced (armored): resist kinking and useful in head and neck surgery 4. Micro-laryngeal tubes 5. Double-lumen ETT (facilitate lung isolation and one-lung ventilation) 6. ETT equipped with bronchial blockers (facilitate lung isolation and one-lung ventilation) 7. Metal tubes: for laser airway surgery 8. Preformed curved tubes for nasal and oral intubation in head and neck surgery b. Laryngoscopes: i. Instrument to examine the larynx and facilitate intubation of the trachea, with the Macintosh and Miller blades being most popular VP ii. Types include: 1. Video laryngoscope: a. Have either a video chip (DCI, GlideScope, McGrath, Airway) or lens / mirror (Airtraq) at the end of the tip of intubation blade b. Proves advantageous for unskilled operators in patients with uncomplicated / complicated airways c. Visualization does not always lead to successful intubation! ETT stylet is recommended when video laryngoscopy is performed to facilitate intubation, where bending the stylet and ETT in a manner similar to the bend in the curve of the blade often facilitates passage of ETT into the trachea 2. Flexible fiberoptic bronchoscopes: a. Allows indirect visualization of larynx in patients with unstable cervical spine, poor range of motion of TMJ, certain congenital anomalies, or acquired airway anomalies. VP b. Constructed of coated glass fibers that transmit light and images by internal reflection G. Techniques of direct and indirect laryngoscopy and intubation a. Indications of intubation: i. This is not a risk free procedure, not all patients with GA requires this ii. Indicated in patients who are at risk of aspiration and those undergoing surgical procedures involving body cavities, head and neck. iii. Mask ventilation or ventuilation with LMA usually suffice for: 1. Cytoscopy 2. Examination under anesthesia 3. Inguinal hernia repairs 4. Extremity surgery b. Preparations for direct laryngoscopy: i. Check equipment and positioning of the patient ii. TT should be examined and testing cuff inflation using 10mL syringe iii. Some anesthesiologist cut the TT to preset length because: 1. Minimize dead space 2. Risk of bronchial intubation 3. Risk of occlusion from tube kinking iv. Connector pushed firmly into the tube to minimize disconnection v. If using a stylet, it should be inserted into the TT which is then bent to resemble a hockey stick > facilitates intubation of anteriorly positioned larynx vi. Desired blade is locked into the handle and bulb function is tested vii. Extra handle, blade, TT, and stylet, functioning suctioning unit should immediately be available viii. Patient’s head should be level with anesthesiologist’s waist or higher to prevent back strain ix. Moderate head elevation (5-10cm from surgical table) and extension of atlantooccipital joint -> sniffing position. Lower portion of cervical spine is flexed by resting head on pillow or other soft support VP x. Preoxygenation -> administration of 100% O2 -> margin of safety in case patient is not easily ventilated after induction xi. Failing to preoxygenate -> increases risk of rapid desat after apnea xii. GA abolishes patients’ protective corneal reflex! Therefore care must be taken to prevent injury to patient’s eyes by abrading the cornea! c. Orotracheal intubation: i. Laryngoscope is held with left hand, and blade is introduced to right side of oropharynx (avoid the teeth!) with the tongue swept to the left and up into the floor of pharynx ii. Tip of curved blade is inserted into vallecula, and straight blade tip covers the epiglottis iii. Handle is raised up and away from patient perpendicular to patient’s mandible to expose vocal cords iv. Avoid -> trapping lip between teeth and blade or leverage on the teeth v. TT is taken with right hand and its tip is passed through the vocal cords. Backward-upward-rightward-pressure (BURP) procedure can be done to monve an anteriorly positioned glottis posterior to facilitate visualization of glottis. vi. TT cuff should lie in the upper trachea, beyond the larynx vii. While withdrawing laryngoscope, avoid tooth damage! viii. Cuff is inflated with least amount of air to create seal during positive pressure ventilation to minimize pressure damage to trachea (Overinflation >30mmHg may inhibit capilary blood flow of trachea) ix. Immediately ausculate the chest and epigastrium, and put on capnographic tracking (definitive test) to ensure intratracheal VP x. xi. xii. xiii. xiv. xv. xvi. location. If doubt whether tube is in esophagus or trachea, then repeat laryngoscopy Tube is then taped or tied to secure position Capnograph does not exclude possibility of bronchial intubation -> signs of which is often increase in peak inspiratory pressure. Proper tube location can be reconfirmed by palpating the sternal notch while compressing the pilot balloon. Cuff shouldnt be left above the cricoid cartilage for far too long because it can cause post-operative hoarseness and increases the risk for accidental extubation Oral intubation is poorly tolerated by awake and fit patient -> IV sedation, local anesthetic spray in oropharynx, regional nerve block, constant reassurance Kalau gagal, do not try again the same way. Changes must be made to increase likelihood of success -> repositioning of patient, decrease tube size, adding a stylet, selecting different blade, using indirect laryngoscope, attempting nasal rounte, or asistance of another anesthesiologist is necessary If patient is difficult to ventilate with mask, then alternative management (LMA, combitube, cricothyrotomy, tracheostomy) can be done. Bougie can facilitate intubation when ETT cannot be directed into glottis despite good visualization of laryngeal opening. d. Nasotracheal intubation: i. TT is advanced through nostril patient can breathe with– nasopharynx – oropharynx before laryngoscopy ii. Phenylephrine nose drop (0.5% or 0.25%) vasoconstrict vessels and shirnk mucous membranes iii. If patient is awake, then apply local anesthetic ointment (for nostril), spray (for oropharynx), and nerve blocks iv. TT lubricated with water-soluble jelly is introduced along the floor of the nose below inferior turbinate at an angle perpendicular to the face. v. To ensure tube passes along the floor of nasal cavity, the proximal end should be pulled cephalad vi. Proceed until tip can be seen in oropharynx vii. Laryngoscopy reveals the abducted vocal cords and TT is pushed onwards. If there is difficulty, then tip of the tube may be directed with Magill forceps but be careful not to damage the cuffs viii. Great risk if patient has midfacial trauma -> intracranial placement VP e. Flexible fiberoptic intubation: i. Routinely performed in awake or sedated patients with problematic airways ii. Ideal for: 1. Small mouth opening 2. Minimizing cervical movement in trauma or RA 3. Upper airway obstruction (angioedema, tumor) 4. Facial deformities, facial trauma iii. Can be performed awake or asleep via oral or nasal routes 1. Awake: predicted inability to ventilate by mask, upper airway obstruction 2. Asleep: failed intubation, minimal C spine movement in patient who refuse awake intubation 3. Oral: facial, skull injuries 4. Nasal: poor mouth opening iv. Likely add the anesthesia time prior to surgery v. Airway is anesthesized with local anesthetic spray, patient sedation is provided vi. Dexmedetomidine -> advantage of preserving respiration while providing sedation vii. Both nostrils are prepared with vasoconstrictive drops, with dominant nostril being identified. viii. A large nasal airway can be inserted in contralateral nostril with breathing circuit connected to administer 100% O2 during laryngoscopy ix. If patient unconscious and not breathing spontaneously, then mouth can be closed and ventilation attempted through single nasal airway -> MUST CONFIRM WITH CAPNOGRAPHY AND PULSE O2METRY x. The lubricated shaft of FOB is introduced to TT lumen, and make sure that it is straight in alignment! At the distal end of the TT, epiglottis or glottis should be visible. xi. Advanced to within sight of carina (sign of proper positioning), and TT pushed off the FOB xii. Proper TT position is confirmed by viewing tip of the tube at appropriate distance (3cm in adults) above the carina before FOB is withdrawn. f. Surgical airway techniques: i. Required when “cant intubate, cant ventilate” scenario presents ii. Options include: 1. Surgical cricothyrotomy-> incision of CTM to place breathing tube. Seldinger catheter technique is utilized -> catheter attached to a syringe (16 or 14 gauge) is inserted across CTM. When air is aspirated, a guidewire is passed through catheter into trachea. Dilator is passed over the guidewire and breathing tube placed. THE CATHETER MUST BE SECURED, with sufficient outflow of expired air must be assured to avoid barotrauma. Short (1s) burst of O2 to VP ventilate the patient. Patients ventilated this way can develop mediastinal emphysema or subcutaneous emphysema. 2. Catheter or needle cricothyrotomy 3. Transtracheal catheter with jet ventilation 4. Retrograde intubation H. Problems following intubation: a. Detection of end-tidal CO2 remains gold standard to confirm placement of ETT (harus ada cardiac output, ga bisa di pasien CABG or CP bypass) b. Decreasing O2 sat can occur after tube placement, i. often due to endobronchial intubation especially in small children and babies ii. Inadequate O2 delivery (O2 not turned on, patient not ventilated) iii. VQ mismatch (almost any form of lung disease) c. When sat declines, what to do? i. Ausculate patient’s chest to listen for wheezes, rhonchi, rales ii. Breathing circuit is checked iii. Intraoperative chest radiograph needed to identify cause of desat iv. Intraoperative fiberoptic bronchoscopy to confirm proper tube placement and to clear mucous plugs v. Bronchodilators and deeper planes of inhalation anesthetics -> to treat bronchospasm vi. Obese patients can desat due to reduced FRC and atelectasis d. When end-tidal CO2 decline suddenly, what to do? i. Consider pulmonary thrombus or venous air embolism ii. Other causes of sudden decline in CO iii. Leak in the circuit e. Rising end-tidal CO2, what to do? i. Hypoventilation ii. Increased CO2 production -> malignant hyperthermia, sepsis iii. Depleted CO2 absorber iv. Breathing circuit malfunction f. Increase in airway pressure may indicate obstructed or kinked ETT or reduced pulmonary compliance -> suction the ETT to confirm patency and lungs auscultated to detect bronchospasm, pulmonary edema, endobronchial intubation, pneumothorax. g. Decreases in airway pressure: can occur secondary to leaks in breathing circuit or inadvertent extubation VP I. J. Techniques of extubation: a. Most often, should be performed when patient is either deeply anesthetized or awake -> adequate recovery from neuromuscular blocking agents should be established b. Extubation during light plane of anesthesia (antara deep and awake) is avoided because increased risk of laryngospasm c. To differentiate, suction the pharyngeal cavity. If there is reaction (cough, holding breath) means the patient is in a state of light plane. If no reaction, the patient is in a deep state d. Eye opening or purposeful movements imply that the patient is sufficiently awake for extubation -> associated with coughing on the TT i. Increases heart rate ii. Increases central venous pressure iii. Increases arterial blood pressure iv. Increases intracranial pressure v. Increases intraabdominal pressure vi. Increases intraocular pressure vii. Can cause wound dehiscence and increased bleeding viii. Presence of TT in asthmatic patient -> bronchospasm ix. Decrease these effects by administering 1.5mg/kg IV lidocaine 1-2 minutes before suctioning and extubation e. Patient’s pharynx should be suctioned prior to extubation to prevent aspiration of mucous or blood into the lungs f. Ventilate with 100% O2 in case it will be difficult to establish airway after TT removal g. Remember to remove the tape and uncuff the TT prior to extubation, and remove the TT in a single smooth motion Complication of laryngoscopy and intubation: a. Airway trauma i. Tooth damage is common cause of malpractice claims ii. Laryngoscopy and intubation -> sore throat to tracheal stenosis due to prolonged external pressure -> tissue ischemia, inflammation, ulceration, granulation, and hence stenosis. iii. Cuff pressure of 20mmHg is adequte to reduce bloodflow to site by 75%. It can be diminished by hypotension iv. Postintubation croup caused by glottic, laryngeal, or tracheal edema -> serious in children. Efficacy of corticosteroid VP (dexamethasone 0.2mg/kg up to maximum of 12mg) in preventing this is controversial v. Vocal cord paralysis from cuff compression or other trauma to the recurrent laryngeal nerve -> hoarseness and increased risk of aspiration vi. Post-op hoarseness is seen more in obese, difficult intubations, and anesthetic of long duration. vii. Applying water-soluble lubricant or local anesthetic-containing gel at tip or cuff of TT does not decrease incidence! Some research even says otherwise! viii. Smaller tubes (6.5 in women, 7.0 in men) -> fewer complaints of postoperative sore throat ix. Repeated attempts at laryngoscopy can lead to periglottic edema and inability to ventilate with face mask -> deadly!! b. Hypoxia c. Hypercarbia d. Dental and airway trauma e. Tube malpositioning f. Physiological response to airway instrumentation g. Malfunction K. Errors of TT Positioning: a. Unrecognized esophageal intubation -> catastrophic (can cause esophageal rupture, mediastinitis which presents as severe sore throat, fever, sepsis, subcutaneous emphysema) i. Prevented with direct visualization of tip of TT passing through vocal cords ii. Auscultation for presence of bilateral breath sounds and gastric gurgling while ventilating through TT iii. Analysis of exhaled gas for CO2 iv. Chest radiography v. Use an FOB b. Bronchial intubation (right more often than left) i. Unilateral breath sounds ii. Unexpected hypoxia with pulse oxymetry iii. Inability to palpate TT cuff in sternal notch during cuff inflation iv. Decreased breathing-bag-compliance (high peak inspiratory pressure) c. Cuff placement in larynx: laryngeal trauma. Can be identified by palpating the cuff in the thyroid cartilage d. Routine minimal testing includes: auscultation of the chest, routine capnography, and cuff palpation e. If patient is repositioned, then tube placement should be reconfirmed: i. neck extension or lateral rotation -> TT away from carina ii. Neck flexion -> moves tube toward the carina L. Physiological response to airway instrumentation: a. Laryngoscopy and tracheal intubation in light plane -> hypertension and tachycardia b. LMA is associated with less hemodynamic change VP c. Attenuation of hemodynamic changes can be accomplished by: i. IV lidocaine, opioids, B-blockers, or deeper plane of inhalation anesthesia minutes before laryngoscopy ii. Hypotensive agents: sodium nitroprusside, nitroglycerin, esmolol, nicardipine -> effective iii. Cardiac arrhythmias particularly ventricular bigeminy can occur in light plane anesthesia d. Laryngospasm: forceful involuntary spasm of laryngeal musculature caused by sensory stimulation of superior laryngeal nerve i. Triggering stimuli: pharyngeal secretion, passing TT through larynx during extubation ii. Prevented by extubating patient while awake or deeply asleep iii. Treatment: positive pressure ventilation with anesthesia bag and mask 100% O2, or lidocaine IV 1-1.5mg/kg. iv. If laryngospasm persist and hypoxia develops, succinylcholine 0.250.5mg/kg may be required, or perhaps with small doses of propofol v. Can result in negative-pressure pulmonary edema due to large negative intrathoracic pressure e. Aspiration can result from depression of laryngeal reflex due to prolonged intubation and GA f. Bronchospasm -> most common in asthmatic patient and is a clue to bronchial intubation g. Increased intracranial and intraocular pressure. M. Tracheal tube malfunction: a. Polyvinyl chloride may ignite by cautery or laser b. Valve or cuff damage should be excluded prior to insertion c. Obstruction can be caused by kinking, foreign body aspiration, thick secretions in lumen VP