DAFTAR ISI Hal HALAMAN JUDUL ............................................................................................. i HALAMAN PERSYARATAN ............................................................................ ii BERITA ACARA UJIAN SKRIPSI ................................................................... iii HALAMAN PERSETUJUAN ............................................................................ iv HALAMAN PENGESAHAN .............................................................................. v HALAMAN PERSEMBAHAN .......................................................................... vi PERNYATAAN KEASLIAN PENELITIAN .................................................... vii KATA PENGANTAR ....................................................................................... viii DAFTAR ISI ....................................................................................................... xi DAFTAR TABEL ............................................................................................. xiii DAFTAR GAMBAR ......................................................................................... xiv DAFTAR LAMPIRAN ...................................................................................... xv INTISARI .......................................................................................................... xvi ABSTRACT ....................................................................................................... xvii I. PENDAHULUAN ............................................................................................. 1 A. Latar Belakang Masalah .............................................................................. 1 B. Rumusan Masalah ....................................................................................... 5 C. Keaslian Penelitian ...................................................................................... 5 D. Tujuan Penelitian......................................................................................... 6 E. Manfaat Penelitian....................................................................................... 6 II. TINJAUAN PUSTAKA .................................................................................. 7 A. Telaah Pustaka............................................................................................. 7 1. Kenikir ...................................................................................................... 7 2. Gingiva ................................................................................................... 11 3. Maturasi Sel Epitel Gingiva ................................................................... 12 4. Gingivitis ................................................................................................ 16 viii B. Landasan Teori .......................................................................................... 19 C. Hipotesis .................................................................................................... 21 III. METODOLOGI PENELITIAN ................................................................... 22 A. Desain Penelitian ....................................................................................... 22 B. Identifikasi Variabel .................................................................................. 22 C. Definisi Operasional .................................................................................. 23 D. Subjek Penelitian ....................................................................................... 24 E. Alat dan Bahan .......................................................................................... 25 F. Jalannya Penelitian .................................................................................... 26 IV. HASIL PENELITIAN DAN PEMBAHASAN ............................................ 32 A. Hasil Penelitian ......................................................................................... 32 B. Pembahasan ............................................................................................... 38 V. KESIMPULAN DAN SARAN ..................................................................... 44 A. Kesimpulan................................................................................................ 44 B. Saran .......................................................................................................... 44 DAFTAR PUSTAKA ......................................................................................... 45 LAMPIRAN ix DAFTAR TABEL Tabel .................................................................................................................... Hal 1.aKandungan zat dalam kenikir ............................................................................. 8 2. Jumlah sel epitel gingiva dan standar deviasi sebelum dan sesudah berkumur pada kelompok kontrol dan perlakuan. ............................................. 32 3. Hasil uji normalitas sel gingiva pada kelompok kontrol dan perlakuan sebelum berkumur ............................................................................. 33 4. Hasil uji homogenitas sel gingiva pada kelompok kontrol dan perlakuan sebelum berkumur (p<0,05) .............................................................. 33 5. Hasil uji T tak berpasangan berdasarkan jenis sel epitel gingiva sesudah berkumur pada kelompok kontrol dan perlakuan (p<0,05).................. 34 6. Indeks maturasi sel epitel gingiva sebelum dan sesudah berkumur pada kelompok kontrol dan perlakuan. .............................................................. 34 10 DAFTAR GAMBAR Gambar Hal 1. Cosmos caudatus ................................................................................................. 7 2. Sitoplasma sel superfisial .................................................................................. 30 3. Sitoplasma sel basal dan intermediet. ............................................................... 30 4. Gambaran sel epitel gingiva pada kelompok kontrol sebelum berkumur hexetidine 0,1%. ............................................................................................... 35 5. Gambaran sel epitel gingiva pada kelompok kontrol sesudah berkumur hexetidine 0,1%. ............................................................................................... 36 6. Gambar sel epitel gingiva pada kelompok perlakuan sebelum berkumur larutan ekstrak kenikir 5%. ............................................................................... 36 7. Gambaran sel epitel gingiva pada kelompok perlakuan sesudah berkumur larutan ekstrak kenikir 5%................................................................................ 37 11 DAFTAR LAMPIRAN Lampiran Hal I. Surat Kelayakan Etik Fakultas Kedokteran Gigi UGM………...…...51 II. Surat Identifikasi Tumbuhan………………………………………...52 III. Persetujuan Keikutsertaan Subjek Penelitian………………………..53 IV. Profil Responden Penelitian………………………………………....54 V. Analisis Statistik…………………………………………………..…56 12