biologi molekuler dna - Biologi UIN Alauddin Makassar

BIOLOGI
MOLEKULER DNA
Dedicated By
Mashuri Masri, S.Si., M.Kes
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TUJUAN PEMBELAJARAN
1.Defenisi Biologi Molekuler
2. Inti Sel, Kromosom, DNA, Basa
Nitrogen, Gen.
2
Inti Sel
KROMOSOM
DNA
BASA
NIROGEN
AGCT
GEN
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Struktur DNA
4
5
6
Kariotipe Pria
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Kariotipe Perempuan
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Karioptipe Pria
Karioptipe Perempuan
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Kromosom
Kromosom Tubuh
22 pasang
44 buah
Kromosom Seksual
1 pasang
2 buah
(XY)
♂
46
10
Kromosom
Kromosom Tubuh
22 pasang
44 buah
Kromosom Seksual
1 pasang
2 buah
(XX)
♀
46
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12
13
• Three representations of DNA
Hydrogen bond
Ribbon model
Partial chemical structure
Computer model
Figure 10.3D
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inti sel
kromosom
DNA
Gula
Pentosa
Asam
Posfat
Basa
Nitrogen
GEN
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16
17
18
19
20
21
22
23
24
Aturan dasar
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26
27
28
29
30
31
Bagaimana dengan virus genom
RNA ??
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33
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• A specific gene specifies a polypeptide
– The DNA is transcribed into RNA, which is
translated into the polypeptide
DNA
TRANSCRIPTION
RNA
TRANSLATION
Protein
Figure 10.6A
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Gene 1
Gene 3
DNA molecule
Gene 2
DNA strand
TRANSCRIPTION
RNA
Codon
TRANSLATION
Polypeptide
Figure 10.7
Amino acid
36
Huruf kedua
U
Fenilalanin
UCU
UCC
UCA
UCG
C
Serin
Serin
Serin
Serin
UAU
UAC
UAA
UAG
A
Tirosin
Tirosin
stop
stop
UUA
UUG
CUU
CUC
CUA
CUG
CCU
CCC
CCA
CCG
Prolin
Prolin
Prolin
Prolin
CAU
CAC
CAA
CAG
AUU Isoleusin ACU
AUC
ACC
Isoleusin
ACA
AUA Isoleusin ACG
AUG Metionin
Treonin
Treonin
Treonin
Treonin
AAU
AAC
AAA
AAG
GUU
GUC
GUA
GUG
Alanin
Alanin
Alanin
Alanin
GAU Asam
UUU
Hu
ruf
Per
ta
ma
U
Fenilalanin
UUC
C
A
G
Leusin
Leusin
Leusin
Leusin
Leusin
Leusin
Valin
Valin
Valin
Valin
GCU
GCC
GCA
GCG
UGU
UGC
UGA
UGG
G
Sistein
Sistein
stop
Triptofan
U
C
A
G
Histidin
Histidin
Glutamin
Glutamin
CGU
CGC
CGA
CGG
Arginin
Arginin
Arginin
Arginin
U
C
A
G
Asparagin
Asparagin
Lisin
Lisin
AGU
AGC
AGA
AGG
Serin
Serin
Argini n
Arginin
U
C
A
G
GGU
GGC
GGA
GGG
Glisin
Glisin
Glisin
Glisin
U
C
A
G
Aspartat
GAC Asam
Aspartat
GAA Asam
Glutamat
GAG Asam
Glutamat
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Huruf
Ke
Tig
a
REFERENSI
• Triwibowo Yuwono (2005). PCR.
Yogyakarta, Penerbit Erlangga.
• Fatchiyah, Estri L.A., Sri W., Sri
R.,(2011).Biologi Molekuler, Prinsip Dasar
Analisis. Jakarta,Penerbit
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