Slide 1

Asam Nukleat
• Polimer cincin
ribofuranosida yang
dihubungkan oleh gugus
ester fofat.
• Setiap ribosa terikat pada
basa.
• Ribonucleic acid (RNA)
• Deoxyribonucleic acid (DNA)
Chapter 23
=>
2
Ribonucleosides
A -D-ribofuranoside bonded to a heterocyclic
base at the anomeric carbon.
=>
Chapter 23
3
Ribonucleotides
Add phosphate at 5’ carbon.
Chapter 23
4
Structure of RNA
=>
Chapter 23
5
Structure of DNA
• -D-2-deoxyribofuranose is the sugar.
• Heterocyclic bases are cytosine, thymine
(instead of uracil), adenine, and guanine.
• Linked by phosphate ester groups to form the
primary structure.
=>
Chapter 23
6
Base Pairings
=>
Chapter 23
7
Double Helix of DNA
• Two complementary
polynucleotide chains
are coiled into a helix.
• Described by Watson
and Crick, 1953.
=>
Chapter 23
8
DNA Replication
=>
Chapter 23
9
Additional Nucleotides
• Adenosine monophosphate (AMP), a
regulatory hormone.
• Nicotinamide adenine dinucleotide (NAD), a
coenzyme.
• Adenosine triphosphate (ATP), an energy
source.
=>
Chapter 23
10
End of Chapter 23
Chapter 23
11